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KMID : 0614620100560050324
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Korean Journal of Gastroenterology
2010 Volume.56 No. 5 p.324 ~ p.328
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A Case of Psoriasis Induced by Infliximab Treatment for Crohn’s Disease
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Jwa Yoon-Jung
Kim Nam-Hoon
Park Hai-Jin
Park Jun-Sup
Bae Won-Ki
Kim Kyung-Ah
Lee June-Sung
Moon Young-Soo
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Abstract
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Infliximab, the monoclonal antibody to tumor necrosis factor, is indicated for refractory luminal and fistulizing Crohn’s disease and rheumatoid arthritis. Infliximab treatment has adverse events including infusion reactions, opportunistic infections, and the potential for the event such as reactivation of latent tuberculosis. Cutaneous adverse reactions of TNF-α agents include skin rash, urticaria, pruritus, lupus-like eruption, and injection site reactions. Most of all, psoriasis or psoriasiform dermatitis induced by infliximab treatment for Crohn’s disease is rarely reported in Korea. We report a case of psoriasis induced by infliximab treatment for Crohn’s disease with a review of world literature.
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KEYWORD
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Crohn’s disease, Infliximab, Psoriasis
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